Mutate!: A good choice of traits renders this useless.

The psychic nullifier is always available.

Ghost: Even less useful than Silent Death.

Friendly Foe: Poor, poor design choice.

Fortune Finder, Master Trader: Money is not an issue in the game.

Flower Child: Convenience for chem users.

Faster Healing, Healer: Healing rate is never an issue.

Fixit, Speaker: There are enough skill points in the game without the need to waste perks on getting more skill points.

Earlier Sequence: Minimal impact on combat.

Cult of Personality, Presence: The reaction system is broken, rendering these useless.

Animal Friend: Animals are not a threat.

Strong Back: Inventory capacity is hardly an issue, especially with a party member to use as a mule.

Smooth Talker: Diplomat characters will have a good starting intelligence.

Silent Death only affects the first attack made, while Silent Running is a convenience.

Silent Death and Silent Running: Sneaking is poorly implemented and the perks follow the pattern.

Save scumming is effectively mandatory for any sort of normal gameplay, rendering the perk null.

Pickpocket: Failing at stealing causes everyone to turn permanently hostile regardless.

Lifegiver: The impact is negligible due to the level cap and limited number of experience points available.Bonus HtH Damage and Bonus Ranged Damage: The bonus to max damage is too low to make a noticeable effect (short of using burst weapons).Tag!: Can be used on Energy Weapons late in the game.Quick Pockets: Improved access to inventory, but not as useful as the variant in Fallout 2.Dodger and Toughness: Protection is good.Slayer and Sniper: Ultimate combat perks that are usually not available in normal gameplay, due to the extremely high level requirement.More Criticals and Better Criticals: Good pairing in Fallout, as the top perks are only available in the end game, if at all.Bonus Rate of Fire/ Bonus HtH Attacks: Self-explanatory.Awareness: Essential for any sort of planning in combat.A quick breakdown of the usability of perks is as follows: Not all perks are equal due to the way the game is structured. For perks with multiple ranks the benefit listed should be interpreted as 'per rank.'

Fallout new vegas perk tree